Vytrus Biotech Develops Plant Exosomes, Presents Customizable Exosomic Peptides

Vytrus Biotech has leveraged its biotech expertise to develop intact plant exosomes for skin and hair care applications. In relation, it has patented the concept of Exosomic Peptides (i.e., the array of peptides found in exosomes) that can be manipulated for desired skin and hair benefits.

As the company explains, exosomes (aka ectosomes) are small extracellular vesicles (sEVs) bound by a lipid membrane. These hold and protect key "natural biological communicators" — i.e., DNA, RNA, lipids, proteins, cytokines, heat shock proteins, enzymes, antioxidants and other bioactives.

Delving into the depths of these natural entities in plants, the company has refined and developed exosomes including select cocktails of natural plant peptides for anti-aging, anti-inflammatory and anti-wrinkle activities, among others.

See related: Vytrus Biotech Highlights Sun-Microbiota-Skin Axis, Launches Photobiome

Plant Exosomes for Custom 'Cross-kingdom' Communication

Contrary to synthetic and biomimetic exosomes currently available, Vytrus' exosomes are created from actual plants in culture using biotechnology. These exosomes are fully intact and structurally similar to mammalian exosomes that, per the company, "can penetrate and deliver molecular information to human cells very effectively, allowing cross-kingdom communication in cosmetics."

The company's plant cell cultures reportedly show a high exosome concentration vs traditional plant sources (i.e., billions of exosomes/mL). In addition, it is possible to customize and guide the plant cells to produce different kinds of exosomes for skin and hair care.

For example, Vytrus Biotech developed Curcuma longa exosomes to improve skin hydration and regeneration, hair density and hair loss. Also, Centella asiatica exosomes to activate cutaneous genes related to aging, the skin barrier and hydration in keratinocytes (increased expression of type I collagen, inhibition of elastase, etc.), with "powerful regenerative and anti-wrinkle effects on the skin."

See archived: Vytrus Biotech Debuts Elaya Renova for Hair/Scalp 'Tensegrity,' New Brand Identity

Harboring Cosmetic Benefits

According to Vytrus Biotech, plant exosomes can serve multiple cosmetic functions, including:

• anti-inflammation,
• well-aging,
• immunomodulatory,
• healing,
• hydration,
• extracellular matrix protein synthesis,
• protection,
• microbiota modulation,
• skin regeneration; and
• balancing skin homeostasis, among others.

Thus, the exosomes are positioned as functional, sustainably derived ingredients that align with consumer demand for effective natural skin and hair care.