Calybiota® Bio is an eco-designed active ingredient that rebalances the skin microbiota with a prebiotic effect. It is sustainably sourced from the red kapok tree flower calyxes (Bombax costatum) in Burkina Faso. This ingredient is listed under the INCI name Glycerin, Water, and Bombax Costatum Flower Extract. Calybiota® Bio had previously demonstrated its effectiveness in rebalancing women’s intimate flora. Recent clinical research has further revealed that a 1.5% concentration of Calybiota® Bio significantly reduces unpleasant body odors by optimizing the axillary microbiota of men.
Enhancing axillary microbiome health
The skin is home to a complex community of bacteria that plays a critical role in maintaining immune function and barrier integrity. For the skin microbiome to function optimally, it must be maintained in a delicate balance between the quantity and diversity of the microbes it contains. When this balance is disrupted, it can lead to dysbiosis, where harmful bacteria outnumber beneficial ones, resulting in issues like weakened barrier function and unpleasant odors, particularly in the axillary area. Body odor is caused by bacteria on the skin that break down certain compounds in sweat, producing odor molecules. Sweat itself is nearly odorless, but when bacteria decompose the lipids and proteins in sweat, they generate volatile compounds responsible for unpleasant odors.
In a clinical study of 27 men, 1.5% Calybiota® Bio showed a remarkable prebiotic effect on the axillary microbiome. Detailed taxonomic profile analysis has demonstrated that Calybiota® Bio significantly improves bacterial diversity and quantity, enhancing the ratio of Staphylococcus (beneficial species) to Corynebacterium (odor-associated bacteria) by 489% from day 0 to day 27. This suggests that Calybiota® Bio effectively supports beneficial bacteria while mitigating the presence of odor-causing microorganisms, all while preserving the overall microbiome integrity.
Effective odor control
Beyond its role in balancing the microbiome, Calybiota® Bio also helps control axillary odor, as demonstrated in clinical studies. It significantly reduces the presence of volatile organic compounds (VOCs), which are responsible for unpleasant odors. A 1.5% concentration of Calybiota® Bio led to a noteworthy reduction in total VOCs, with a 56.8% decrease observed after just 24 hours compared to the placebo. This includes substantial reductions in specific VOCs such as acetic acid, butyric acid, and valeric acid—compounds known for their distinct and undesirable odors. This efficacy underscores Calybiota® Bio's potential in enhancing axillary hygiene and providing effective odor management.
Versatile applications and broader benefits
Calybiota® Bio's benefits extend well beyond the axillary area. It is highly recommended for intimate hygiene care, with clinical studies confirming its protective and prebiotic effects on vaginal flora (L. gasseri, L. acidophilus, L. jenseni). Calybiota® Bio alleviates discomfort, soothes, and hydrates the intimate area, thus improving the sexual well-being of women, particularly post-menopausal women.
It has also been tested in vitro against various pathogens associated with skin issues, including:
- S. aureus: Atopic dermatitis
- C. acnes, M. furfur : Acne and seborrheic dermatitis
These applications highlight its versatility in addressing a range of skin concerns by targeting the microbiome. Calybiota® Bio is 100% natural, COSMOS certified, and sourced from the calyxes of red kapok tree flowers. The red kapok tree is an oxalogenic species, meaning it utilizes the 'oxalate-carbonate pathway' in its metabolism to form calcium carbonate in the soil, contributing to one of the most sustainable forms of carbon sequestration. Grown in protected areas of Burkina Faso, the calyxes are harvested by workers trained in best practices, underscoring our commitment to sustainability and efficacy. With benefits extending from intimate care to effective odor management, Calybiota® Bio is a valuable ingredient in skincare formulations.
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