University of California School of MedicineArticles & NewsMagazineIndustry Insight: Stress vs. Strain, and Cosmetics to Enhance an Alternate RealityThis "Industry Insight" is adapted from an interview with John Koo, M.D., a dermatologist and psychiatrist, and professor of dermatology at the University of California, San Francisco School of Medicine, about the mind-skin-emotion connection.Method/ProcessCeramides in Skin Stress: Ultraviolet, Tape Stripping, and CrowdingStress induces changes in the ceramide content of the skin, and may lead to compromised barrier function or skin diseases. Skin has ways of responding to these stresses, as we review here in the case of skin stressed by tape stripping, organic solvents, overcrowding, and ultraviolet (UV) irradiation.