Symrise's Organic SymCalmin Avena Targets Histamine Release & Redness to Soothe the Skin

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Symrise's new organic-oat-derived SymCalmin Avena (INCI: maltodextrin (and) Avena sativa (oat) kernel extract) is designed to soothe sensitive skin from symptoms such as itching or feelings of tension and stinging.

The organic product comprises a high level of avenanthramides (200-250 ppm), per the company. 

A paper from the University of Torino in Italy reported in 2018 that, "A number of studies demonstrate that these natural products [avenanthramides] have strong antioxidant activity both in vitro and in vivo, as well as anti-inflammatory, anti-itching, anti-irritant, antiatherogenic, and antiproliferative activities, which may prevent or limit cellular oxidative dysfunctions and the development of oxidative stress-related diseases, such as neurodegenerative and cardiovascular diseases, and provide additional protection against skin irritation, aging, CHD, and cancer."

Derived from German-grown oats processed regionally, SymCalmin Avena—in addition to soothing the skin of itching, tightness or redness—helps to regulate its moisture balance to prevent dryness.

The technology works by targeting the mast cell receptor MRGPRX2, which is associated with itchy and irritated skin due to its interaction between nerves and the immune system.

By reducing the release of histamine, SymCalmin Avena is reportedly able to alleviate itching, while visibly reducing the appearance of skin redness after a period of one to two weeks.

SymCalmin Avena's avenanthramide content is extracted from organic oats via the company's SymTrap technology, which leverages natural solvents.

While its efficacy is on par with conventional alternatives already on the market, the technology is reportedly unique in its COSMOS organic certification.

The neutrally colored technology is recommended for a wide range of applications, including skin and body care and hygiene products.

"Symrise consistently commits to sustainability," said Lili Baraton, global product manager soothing actives at Symrise. "It forms the core of everything we do. Thus, we feel proud to offer our customers this organic active ingredient with patented effect for sensitive skin. In this way, we support brand manufacturers and their ranges of cosmetics with natural and certified organic ingredients. Among other things, for SymCalmin Avena, we have established a cooperation with local farmers who supply us with organic oats. Short distances improve our CO₂ balance because we process the ingredients in geographic proximity to the producer."