Path Uncovered to Create Dermal Papilla-like Cells and Advance Hair Follicle Growth

Oct 6th, 2020

Rachel Grabenhofer

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Upcoming work, to be published in Applied Materials Today, describes how a team of researchers from Chinese universities converted dermal fibroblasts to dermal papilla cell-like structures. This finding could advance hair loss and growth research.

According to the article abstract, new sources for human dermal papilla cells (hDPCs) are crucial to advancing hair follicle regeneration strategies. Here, the authors used alginate-poly-L-lysine-alginate (APA) microcapsules to transform human dermal fibroblasts (hDFs) into hDPC-like cells.

See related: Skin Rashes and Hair Loss, Biological Connectsion to COVID-19

The resulting cells were reportedly comparable to native DPCs. They also were shown to induce the formation of hair follicle-like structures and hair pigmentation in animal models.

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[podcast] How RNA Sequencing Advances Claims Support

RNA sequencing is a newer, more dynamic approach than DNA sequencing to measure the effects of ingredients and products on skin. Rishabh Kala, Ph.D., of Genemarkers, explains its capabilities in this sponsored podcast. Listen now; it's free.

Using an oil blotting film to collect facial sebum, Kao can apply skin surface lipids-RNA monitoring technology to 'infer' skin and physical conditions such as pediatric atopic dermatitis and Parkinson's disease.

Kao's New Infant Sebum Testing Protocol Can Flag Atopic Dermatitis, Parkinson's Disease

The move is the start of Kao's expansion into health testing services.

In evaluating how different solvents may affect the rheology of personal care formulas, it is helpful to consider that different formulation types have distinct relationships between viscosity and elasticity depending on the factors generating their elastic properties.

How Natural Butylene Glycol Advances Market and Rheology Dynamics

Demand for sustainable ingredients in cosmetics and personal care is well-known. Here, a sustainable natural butylene glycol is described to advance this trend and its effects on viscosity and elasticity are assessed in five test formulas.

Lucas Meyer Cosmetics CT Branded Content 10-07-24

Lucas Meyer Cosmetics CT Branded Content 10-07-24

The authors believe that adding the properties of a wide range of commercial sunscreens to the system database will increase the rate of appropriate sunscreen usage by customers.

AmorePacific, Hanyang Univ. Dynamically Visualize UV Dose on SPF-protected Skin

Work by AmorePacific and Hanyang University, Seoul, published in Skin Research & Technology, reveals a dynamic approach to visualize UV dose based on MED, weather, outdoor activity, etc., on SPF-protected skin.

To prevent and repair UV-induced skin damage, a sustainable ingredient was developed from Sargassum vulgare, a brown seaweed that naturally evolved phlorotannins to defend against UV damage. The algae was fermented using a proprietary yeast to enrich this bioactive content; the resulting ingredient was tested as described here for skin benefits.

Brown Seaweed Ferment Propagates UV Damage Protection for Skin

To prevent and repair UV-induced skin damage, a sustainable ingredient was developed from Sargassum vulgare, a brown seaweed that naturally evolved phlorotannins to defend against UV damage.

The model accurately predicted skin permeability and the speed of the UHPLC method could classify it as a high-throughput approach.

Test Model Developed to Predict Skin Permeability of Compounds

A test model published in the Journal of Chromatography A uses retention on octadecyl, cholesterol-bonded and immobilized artificial membrane columns to accurately predict the skin permeability of compounds.

The Dermial ingredient, a hyaluronic acid matrix ingredient for skin and beauty, delivers better results for skin health over standard hyaluronic acid (HA) in nutricosmetic form.

Bioiberica’s Dermial Nutricosmetic Outperforms Extracted and Fermented HAs

A pre-clinical in vitro study showed the Dermial hyaluronic acid (HA) matrix nutricosmetic increased type I collagen production by almost half. According to Bioiberica, this has not been seen with standard extracted or fermented HAs.

For multifunctional products such as moisturizing hand sanitizers, the sanitizer claim requires a significant reduction (2-3 log) of a microorganism population while the moisturizer claim requires data showing an increase in skin moisture.

Testing the Safety and Efficacy of Multifunctional Personal Care Products, A Primer

Multifunctional products may offer solutions to consumer challenges but as the needs of consumers grow more complex, so do their safety and efficacy testing. This article provides a primer on these considerations.

Silicones are widely used as binders in pressed powders but growing consumer skepticism has prompted the use of alternatives. The aim of this study was to assess the efficacy of three plant-derived natural binders in obtaining optimal pressed powders, using dimethicone as a standard.

‘Pressed’ for Powders: Replacing Dimethicone with Plant-derived Alternatives*

The aim of this study was to assess the efficacy of three plant-derived natural binders in obtaining optimal pressed powders, using dimethicone as a standard.

Eurofins Ct2203 Lead

Reduction of skin stress by CBD products: Aiming high above the competition

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